100 Years of Human Chorionic Gonadotropin: Reviews and New Perspectives, 1st Edition

100 years of Human Chorionic Gonadotropin: Reviews and New Perspectives - is a collection of articles written by some of the world's leading experts on the pregnancy hormone and cancer marker h CG.

In 2019 it is difficult to ignore the effect that our understanding of h CG has had on the lives of millions of people worldwide. The h CG immunoassay, in one form or another, is now one of the most common medical tests conducted and is often the first indication that a mother-to-be is pregnant. Not only a marker of pregnancy, h CG is utilized in the diagnosis and monitoring in oncology and presents a potential target for novel cancer therapeutics.100 years ago, in 1919, Hirose was demonstrating gonadotropic functions which resulted from a chorionic factor.

Over the last century this factor has become defined as h CG and more recently explored as not one molecule but a group of molecules with variable structure and variable functions in both pregnancy and cancer. h CG is a multi-faceted molecule that has clinical and therapeutic implications but can be a challenging topic for researchers and physicians alike.

This text covers the different structures and functions of h CG exploring the genes and evolution of the molecule, the different protein and glycosylation structures which can exist and their effect on structure, detection and quantification.100 Years of h CG is not an attempt to recount the history of every publication on h CG, but rather a collection of reviews and new perspectives by "h CG-ologists", the term used by Hussa to describe biochemists working on HCG in the first book written on the topic over 30 years ago.

Some of the authors have been around a while, some not so long, but others are just beginning their journey with a most beguiling molecule.

Book Details

• Authors: Laurence A. Cole, Stephen A. Butler
• Publisher: Elsevier (S&T)
• Edition: 1st Edition
• eBook ISBN: 9780128216095, 0128216093
• Print ISBN: 9780128200506, 0128200502